The following is a summary of “An Investigation of Corticospinal Tract Microstructural Integrity in ARSACS Using a Profilometry MRI Analysis: Results From the PROSPAX Study,” published in the April ...

Background Evaluation of the structural integrity and functional excitability of the corticospinal tract (CST) is likely to be important in predicting motor recovery after stroke. Previous reports are ...

This indicates that T1-relaxation times along the corticospinal tract can be used as a quantitative marker for disease activity in ALS, while commonly used MRI imaging is often unremarkable.

Background Traumatic spinal cord injury (SCI) leads to disruption of axonal architecture and macroscopic tissue loss with impaired information flow between the brain and spinal cord—the presumed basis ...

Movement is a complex process governed by a network of neuronal circuits spread across multiple regions of the nervous system ...

Stroke patients commonly face challenges during magnetic resonance imaging (MRI) examinations due to involuntary movements. This study aims to overcome these challenges by utilizing multiple ...

Unilateral brain injuries occurring before at or shortly after full-term can result in hemiplegic cerebral palsy (HCP). HCP affects one side of the body and can be characterized in the hand with ...

We used diffusion MRI and tractography to investigate the relationship between structural morphology of the supraspinal corticospinal tract (CST) and the severity of two typical hand impairments ...

The corticospinal tract (CST) is a major neural pathway that is associated with post-stroke motor outcomes (8). It travels through the cerebral crus and the anterior part of the pons that are supplied ...

Background and Purpose— Whether patients with small perfusion lesions benefit from thrombolysis remains an uncertainty. We assessed acute ischemic stroke patients with a total perfusion lesion of ...