eLife3mon
A human forebrain organoid model reveals the essential function of GTF2IRD1-TTR-ERK axis for the neurodevelopmental deficits of Williams syndrome
Zhao et al. report valuable adverse effects on cell proliferation, differentiation and gene expression, possibly linked to reduced binding activity of the transcription factor GTF2IRD1 to the ...
Frontiers2y
Phenotype and Distribution of Immature Neurons in the Human Cerebral Cortex Layer II
These immature cells belonged to the excitatory lineage, as demonstrated both by the expression of CUX1, CTIP2, and TBR1 transcription factors and by the lack of the inhibitory marker GAD67. The type ...
eLife4y
A discrete subtype of neural progenitor crucial for cortical folding in the gyrencephalic mammalian brain
An increase in the diversity of neural progenitor subtypes and folding of the cerebral cortex are characteristic features which appeared during the evolution of the mammalian brain. Here, we show that ...
Frontiers11y
Direction- and distance-dependent interareal connectivity of pyramidal cell subpopulations in the rat frontal cortex
After washing in TBS, the sections were reacted with secondary antibodies conjugated to Alexa Fluor 594 (for VGluT2) and Alexa Fluor 488 (for Ctip2). The sections were mounted on glass slides, ...