The following are the steps in the cycle: The Krebs cycle enzymes are membrane proteins found within the matrix of the mitochondria except for succinate dehydrogenase which is an integral membrane ...

The screening led to the identification of the TCA cycle enzyme DLST as an important contributor to T-cell acute lymphoblastic leukemia development. Further analysis using human T-cell leukemia ...

Researchers have new insights into the citric acid cycle: Certain bacteria can use this central metabolic pathway 'backwards', but to do so they must have very high concentrations of the enzyme ...

The discovery that a version of the Krebs cycle, which occurs in most living cells, can proceed in the absence of cellular proteins called enzymes suggests that metabolism is older than life itself.

Researchers at Duke University Medical Center and Wake Forest University School of Medicine have identified ALDH4A1, a mitochondrial proline-metabolizing enzyme ... import for TCA cycle entry ...

Two simple molecules can react to form most of the intermediates in an analog of the modern-day Krebs cycle, without the need for enzymes or metals, according to a new study (Nat. Chem.