how does binding of ephrin lead to activation of the Eph receptor? To understand the mechanism in detail, it will be necessary to determine the structures of Eph receptor family members ...

Eph receptors and their membrane-bound ephrin ligands are expressed in complementary segments of the hindbrain. Signalling between these receptors and ligands is sufficient to establish a sharp ...

These findings suggest that disruptions in Ephrin B2/EphB4 signaling might be ... FCCMs through clinical findings, imaging, and family history, genetic testing can identify pathogenic variants ...