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Microglia are required for developmental specification of AgRP innervation in the hypothalamus of offspring exposed to maternal high-fat diet during lactation eLife 13:RP101391.

People with certain genetic variants of this gene should be especially careful to minimize saturated fat because they can gain weight easier from a diet that’s high in it.

Eating a high-fat diet containing a large amount of oleic acid—a type of fatty acid commonly found in olive oil—could drive obesity more than other types of dietary fats, according to a study ...

High-fat diets rapidly deplete IL-22, weakening gut defenses and triggering silent inflammation. Unsaturated fats may help restore IL-22 and protect against chronic disease. A study led by researchers ...

Researchers find high-fat diets set off metabolic dysfunction in cells, leading to weight gain, but these effects can be reversed by treatment with an antioxidant.

Consuming a high-fat diet can lead to a variety of health problems - not only weight gain but also an increased risk of diabetes and other chronic diseases.

A new study has found that after just a few days of eating a high-fat diet, the gut’s defenses are broken down, and an asymptomatic inflammation is triggered that can develop into a long-term ...

Hypothermia and swimming have been shown to alleviate high-fat diet (HFD)-induced obesity, with effects linked to the gut microbiota (GM). However, whether the effects of cold water swimming (CWS) on ...