Background: Although intrapartum antimicrobial prophylaxis has lowered the incidence of early onset group B Streptococcus (GBS) sepsis, there are concerns that the increased use of antibiotics may ...

Gestation at <37 weeks, duration of membrane rupture of ≥18 hours, or temperature of ≥100.4 ºF (≥38.0 ºC) are clinical indications for intrapartum prophylaxis if the GBS status is unknown ...

Nearly half of case-infants (47%) were exposed to intrapartum antibiotics, most often for GBS prophylaxis (56%), caesarian section prophylaxis (6%), or suspected chorioamnionitis (6%). In 127 ...