Cells change their metabolic profiles in response to underlying gene regulatory networks, but how can alterations in metabolism encode specific transcriptional instructions? Here, we show that forcing ...

Find more information on the Altmetric Attention Score and how the score is calculated. The microgel single-cell culture approach we developed to expand tumor stem cells (TSCs) is associated with ...

Anti-PD-1 antibody monotherapy or anti-PD-1 antibody combination with chemotherapy treated non-small cell lung cancer (NSCLC) patients with EGFR mutation: A retrospective analysis. This is an ASCO ...

Lauren Giella is a Senior Reporter based in New York. She reports on Newsweek's rankings content, focusing on workplace culture, health care and sustainability, profiling business leaders and ...

AbCellera’s ‘408 Patent is directed to microfluidic devices and using such devices to culture and selectively recover cells. Previously Berkeley Lights Inc., now Bruker Cellular Analysis ...

Get Instant Summarized Text (Gist) Generative AI has been used to design synthetic DNA regulatory sequences that precisely control gene expression in healthy mammalian cells. These AI-generated ...

A patent for the process has been filed. “Cell culture innovation is crucial for advancing modern medicine, drug discovery, and understanding complex biological systems,” said Dr. Hatim Hemeda, Chief ...

A French research team from Institut Curie, the CNRS and Inserm has just developed a new class of small molecules that bring about the destruction of cell membranes, and hence triggers cell death ...

Emerging techniques for mapping mRNAs within the subcellular compartments of live cells hold great promise for advancing our understanding of the spatial distribution of transcripts and enabling the ...

For the first 4 days of culture, 10 mM Y-27632 (Nacalai Tesque) was added to the medium. Mouse pancreatic ductal organoids were prepared as previously described (Kimura-Nakajima et al., 2021).