Another promising approach is the development of curative combinations. These combinations combine different therapies, such as antiviral drugs and immune-based therapies, to achieve a cure for HBV.

Late-breaking data from BRII-835 + PEG-IFN-a study demonstrate anti-HBs titers at the end of treatment were associated with sustained HBsAg loss 2 ...

Approximately 70% of previous nonresponders to the HBV vaccine developed a response after HCV treatment and cure. Age, HIV status and fibrosis degree did not seem to impact vaccine response.

Hepatitis B e-antigen seroconversion in childhood and low hepatitis B surface antigen titers after seroconversion independently predicted functional cure in chronic HBV-infected patients followed ...

The phase 2b B-Clear study enrolled 457 patients with chronic HBV; 227 were receiving NA therapy, and 230 were not. Participants were randomly assigned to receive weekly subcutaneous injections of ...

Hepatitis B virus (HBV) remains a major public health concern despite effective vaccines. ... Roca Suarez AA, Zoulim F. Opportunities and challenges for hepatitis B cure.

Chronic hepatitis B virus (HBV) infection continues to pose a major global health threat. Home ... the researchers hope to uncover new pathways for a functional cure for chronic hepatitis B.

Drug combination reaches key threshold for 'functional cure' of chronic liver infection that affects more than 250 million people worldwide An international team of researchers led by Chinese ...

Virion Logo (PRNewsfoto/Virion Therapeutics, LLC) These Phase 1b data, on the first 27 chronically infected hepatitis B patients, on nucleos(t)ide antiviral therapy, all of whom received a single ...

By combining these strategies with current antiviral treatments, researchers could significantly enhance their effectiveness, bringing us closer to a functional cure for chronic hepatitis B.

As an oral drug administered once weekly, DF-006 has the potential to be the immunomodulator of choice in combination HBV cure regimens”, said Dr. Ed Gane, Professor of Medicine at the ...