Solid tumors that originate in the deep internal organs, such as the pancreas, liver, and ovary, have poor prognoses due to the difficulties of diagnosing ...

Gene editing is already being used to treat a handful of rare genetic diseases; however, most therapies involve breaking or ...

A study published in Science Advances reveals a novel strategy that allows tumors to evade the body's immune response ...

As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

Activation of hepatic stellate cells is the central event in hepatic fibrosis. These perisinusoidal cells orchestrate an array of changes including degradation of the normal ECM of liver ...

Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an oestrogen independent manner. Targeting vimentin and/or the long ...

Researchers describe successful tumor removal through the use of immunotherapy and targeted radiation therapy (TARE), in a patient previously considered ineligible for the procedure.

Scientists at UC San Francisco have pioneered a groundbreaking approach to fighting cancer using engineered fat cells. By ...

Gene editing is already being used to treat a handful of rare genetic diseases; however, most therapies involve breaking or ...

Oncolytic viruses (OVs) are viruses that infect and kill cancer cells while sparing healthy tissue, making them a promising therapeutic option in cancer ...

az.vub.ac.be Accumulating evidence suggests that stellate cells are involved in the regulation of the liver microcirculation and portal hypertension. Activated hepatic stellate cells have the ...

A partial remission, which means the cancer has shrunk, but the cancer cells are still detectable. Even after a complete remission, cancer cells can remain in the body. This means the cancer can ...