Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an oestrogen independent manner. Targeting vimentin and/or the long ...

School of Physics and Electronics, Key Laboratory of Low-dimensional Quantum Structures and Quantum Control of the Ministry of Education, Institute of Interdisciplinary Studies, Key Laboratory for ...

Treatment may include surgery, a liver transplant, ablation therapy (a needle or probe is used to kill cancer cells), embolization therapy (cutting off blood supply to a tumor), oral targeted agents, ...

After treating a tumor with chemotherapy and radiotherapy, cells known as senescent cells can appear. These are cells that do not divide, are involved in the aging process and are resistant to ...

TLSs are thought to recruit and activate naive T and B cells within the tumor microenvironment (TME) via chemokine signaling, contributing significantly to the complex interplay of immune cells and ...

Salk Institute researchers found that regulating bile acids—specifically reducing harmful ones and increasing UDCA—can enhance T cell function and potentially make immunotherapy more effective for ...

The team demonstrated this both in mouse liver cancer cells and in several human cancer cell lines. The findings are published in the journal Nature Metabolism. However, when the researchers ...

The TP53 gene is a gene that is mutated in many cancers. It is the most common gene mutation found in cancer cells. A tumor-suppressor gene, TP53 codes for a protein that inhibits the development and ...

Long classified as a subset of common liver cancer, FLC should be considered ... That is the true origin of the disease. FLC tumor cells essentially have a molecular imbalance: too many catalytic ...

The tissue adjacent to a tumor behaves differently than areas farther away: The tumor’s cancerous cells influence their surroundings ... “Traditional therapies target one molecule in the tumor ...

A new report points to a notable increase among U.S. women under 50. Experts point to a few likely causes. By Nina Agrawal Siobhan Donovan was a runner who ate her vegetables, didn’t smoke and ...