Fatty liver disease affects more than 1 in 3 adults and often has no symptoms. A new drug developed with Tulane researchers ...

Hepatic stellate cells (HSCs) are activated to heal the liver when it has a lesion (such as fibrosis or fatty liver); their function is to protect the liver by producing an extracellular matrix ...

Researchers have found that stellate cells – known for their role in liver fibrosis – play a key role in protecting and sustaining liver organization and function.

The actual functions of this cell type have hardly been studied to date. Researchers have now determined that hepatic stellate cells control liver metabolism as well as liver regeneration and size.

Hepatic stellate cells are located along the specialized blood capillaries of the liver, known as sinusoids. They are known to drive liver fibrosis, but their actual physiological functions and ...

The activation of hepatic stellate cells (HSCs) is a key process in the pathogenesis of liver fibrosis, but the molecular mechanisms behind it are not fully understood. By combining the analysis of ...

Non-alcoholic fatty liver disease (NAFLD) has emerged as a leading cause of chronic liver disease worldwide, affecting approximately 38% of the global population from 2016 to 2019.

A study conducted in mice and human cell samples suggests that a pharmacological intervention may help reverse age-related liver damage.