Due to the small size and height of the Eva1 molecule, Eva1CAR-T cells can form more effective immune synapses—contact zones between an immune cell and its target tumor cells. The formation of robust ...

Miliotis, a PhD student in the Pharmaceutical Sciences and Pharmacogenomics (PSPG) Program, beat out 10 finalists at Byers ...

This article explores the current landscape and future potential of cell therapies, including CAR T-cell and stem cell-based ...

The immunological synapse can be defined as the orderly rearrangement of molecules in an immune cell at the interface with another cell. In natural killer (NK) cells, the lytic immunological ...

2 Reassessing perforin-independent versatility of GzmB in immune responses Natural Killer (NK ... In the canonical model, GzmB is delivered into target cells through the immunological synapse in a ...

Researchers have discovered that these bacteria specifically target iron-rich regions within immune cells to replicate. Their findings on how pathogens evade the immune defense are important for ...

Then they used CAR T cell therapy to train the body's immune system to look for that synthetic antigen and destroy the marked tumor cells. "Tumor cells are sneaky. Most of the time, immune cells ...

Personalized medicine is going to become very necessary,” she added. One pathway to long covid may be through immune system dysfunction, where the “immune system goes haywire,” Topol said.

Recent advancements have highlighted the intricate interplay between immune cell infiltration patterns, immune checkpoint dysregulation, and metabolic reprogramming in driving HNSCC immune escape.

A decades-long scientific challenge in HIV vaccine development has been finding a way to train the immune system to produce antibodies that can target many variants of the virus. Traditional ...

They inspire us to explore places like the ocean, while improving memory and immune functions. Encountering the new, the interesting, the unexpected, and the “wow!” is built into our brains.