Integrins are heterodimeric structural proteins of the plasma membrane and are principally involved in cell–cell relationships in tissues and cell–extracellular matrix (ECM) protein interactions (1).

With his new Major League Baseball (MLB) collection, Takashi Murakami is aiming to build on what he sees as the “historical friendship between Japan and the United States.” You'll be able to ...

This study aimed to investigate the protective effect of metformin on trabecular meshwork (TM) and explore its molecular mechanisms in vivo and in vitro. Ocular hypertension (OHT) mouse models were ...

We investigated the therapeutic potential of targeting integrin/FAK-dependent signaling, an adhesion receptor-mediated pathway that has been increasingly linked to non-small cell lung cancer (NSCLC) ...

Metastasis depends upon cancer cell growth and survival within the metastatic niche. Tumors which remodel their glycocalyces, by overexpressing bulky glycoproteins like mucins, exhibit a higher ...

A study demonstrates that controlled integrin binding on a biomaterial was capable of promoting vascular cell sprouting and formation of a non-leaky blood vessel network in a healthy and diseased ...