Interleukin-targeting biologics associated with lower infection rates in older psoriatic patients
Department of Medicine, University of Toronto, Women's College Hospital, and co-authors have found biologics targeting ...
FDA approves Tremfya for active Crohn's disease in adults
The U.S. Food and Drug Administration has approved Johnson & Johnson's Tremfya (guselkumab) for adult patients with ...
BioWorld5d
Roche discloses new NLRP3 inflammasome inhibitors
Scientists from F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. have patented NLRP3 inflammasome and interleukin-1β (IL1B; IL-1β) release inhibitors reported to be useful for the treatment of ...
Protagonist Therapeutics Named to Fast Company’s Annual List of the World’s Most Innovative Companies of 2025
Fast Company's annual list of the World's Most Innovative Companies spotlights organizations across various industries that are driving meaningful change through groundbreaking ideas and ...
Frontiers25d
Distinct roles for interleukin-23 receptor signaling in regulatory T cells in sporadic and inflammation-associated carcinogenesis
Introduction: The pro-inflammatory cytokine interleukin-23 (IL-23 ... accessible at webgestalt.org was utilized with their default parameters. The input was a list of all genes sorted on fold change ...
ALZFORUM9mon
Low Dose Interleukin-2
Low dose interleukin 2 is being tested as an immunomodulatory approach in neurodegenerative diseases. It increases the number and activity of regulatory T cells (Tregs) that suppress inflammation. At ...
eLife2y
Interleukin-33 regulates the endoplasmic reticulum stress of human myometrium via an influx of calcium during initiation of labor
Inflammation is currently recognized as one of the major causes of premature delivery. As a member of the interleukin-1β (IL-1β) family, interleukin-33 (IL-33) has been shown to be involved in normal ...
SciELO2y
Serum levels of interleukin-2 differ between prostate cancer and benign prostatic hyperplasia
interferon-γ (IFNγ), interleukin-1β (IL1β), IL2, IL4, IL6, IL8, IL10, IL12.p70, tumor necrosis factor- α (TNFα) and C-reactive protein. Briefly, the lyophilized cytokine standards and the serum ...
Frontiers6y
Excessive Iron Availability Caused by Disorders of Interleukin-10 and Interleukin-22 Contributes to High Altitude Polycythemia
The correlation analysis indicated that the decreased hepcidin may have contributed to enhanced iron availability in HAPC, and decreased interleukin (IL)-10 and IL-22 were significantly associated ...