A study conducted by a research team from Kumamoto University has shed light on the critical role of a tRNA methylation enzyme, TRMT10A, in supporting brain function. The findings reveal how the ...
Northwestern Medicine investigators have discovered previously unknown metabolic changes that may contribute to the ...
DNA methylation is one of several epigenetic mechanisms ... Likewise, demethylated DNA does not attract deacetylating enzymes to the histones, allowing them to remain acetylated and more mobile ...
With RRBS, scientists enrich for GC-rich parts of the genome by digesting the DNA with an enzyme that generates fragments with CpG dinucleotides at both ends, independent of methylation status. This ...
Liver TET1 was found to promote metabolic dysfunction-associated steatotic liver disease (MASLD) by regulating CD36 ...
In this case, adjust the digestion conditions in Step 11 as follows: prepare a final reaction volume of 200 μl, include 7 μl McrBC enzyme and adjust the volumes of GTP, BSA and buffer to achieve ...
This rather complex six-protein system is interesting because it combines classical DNA methylation with new antiviral mechanisms. In this study, we tried to find out how BREX distinguishes ...
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