Myeloid deficiency of the mitochondrial transacetylase tafazzin upregulates mtROS, disrupting UPR and calcium homeostasis, ...

Figure 1. The main mechanism of neutrophils in combating pathogens. When neutrophils come into contact with opsonized pathogens, phagocytosis is initiated. Firstly, neutrophils extend pseudopodia and ...

In multicellular organisms, and more particularly in animals with a well-developed immune system, phagocytosis is mostly performed by specialized, professional phagocytes: macrophages, dendritic cells ...

Novel therapeutic targets and approaches are needed to improve outcomes. Neutrophils are the most abundant immune cell and among the first responders to infection. Appropriate neutrophil responses are ...

The potential benefits of Brewer's yeast include treating diabetes, irritable bowel syndrome (IBS), and respiratory ailments such as the common cold and the flu. It is also used in alternative ...

The impact of Card9 deletion on neutrophil function was assessed by an in vivo model of fungal infection and various functional assays, including endpoint dilution assay, apoptosis assay by flow ...

Yeast infections on the scalp are caused by an overgrowth of fungal organisms. Candida is the yeast that most often infects the scalp. The problem can also be caused by Malassezia, a yeast that often ...

Neutrophils are major players in innate immune system. Here, we aimed to explore the heterogeneity and pro-tumour mechanisms of neutrophils in PDAC. Design We analysed single-cell transcriptomes of ...