The research field of 'cellular IRESes' lay dormant for decades, as there was no uniform standard of reliable methods for the clear characterization of these starting points for the ribosome-mediated ...

Only recently has the ribosome - one of the oldest molecular machines in evolutionary terms - been recognized as an active regulator of gene expression at the level of protein biosynthesis. This is an ...

Only recently has the ribosome—one of the oldest molecular machines in evolutionary terms—been recognized as an active ...

Translation is the process by which a protein is synthesized by the ribosome, using a messenger RNA (mRNA) template. Translational control is emerging as a key regulator of cancer. The RNA-binding ...

In a surprising turn of events, an international team of scientists has found that lead-208 (208 Pb), the heaviest known "doubly magic" nucleus, exhibits unexpected shape characteristics that ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Clustered regularly interspaced short ...

Version of Record: This is the final version of the article. Here the authors convincingly identify and characterize the SERBP1 interactome and further define its role in the nucleus, where it is ...

Ubiquitin Binding Protein 2-like (UBAP2L, also known as NICE-4) is a ubiquitin- and RNA-binding protein, highly conserved in metazoans. Despite its abundance, its functions have only recently started ...

The IAEA offers a wide spectrum of learning and training activities, as well as educational resources and capacity-building programmes. These include face-to-face training courses and workshops, ...

Spatial clustering of ribosomal proteins (r-proteins) through tertiary interactions is a striking structural feature of the eukaryotic ribosome. However, the functional importance of these intricate ...