Oncogene aims to make substantial advances in our knowledge of processes that contribute to cancer by publishing outstanding research. We propagate work that challenges standard conjecture and ...

In their effort to answer a decades-old biological question about how the hepatitis B virus (HBV) is able to establish infection of liver cells ...

American Journal of Pathology, 146, 56-66. [13] Tomasek, J.J., et al. (2002) Myofibroblasts and mechano-regulation of connective tissue remodelling. Nature Reviews Molecular ... New wirings in the ...

serving as a foundation for the now widely accepted phenomenon called oncogene addiction 11. But the euphoria of blast-crisis remissions was short lived. Despite continued imatinib treatment ...

Pancreatic cancer is a disease in which malignant cells originate in the pancreatic tissue. Cancer of the exocrine component of the pancreas (adenocarcinomas) represents the majority of pancreatic ...

An oncogene is a gene that will transform a cell in culture. Oncogenes were initially identified in cancer-causing retroviruses. Genes involved in the regulation of cell division, movement and ...

It is characterized by a series of genetic and cellular changes, including oncogene activation, that lead the cell to divide in an uncontrolled manner. Alveolar bone resorption (ABR) is a key ...

The oncogene MYC plays a key role in cancer initiation and progression. Using thousands of CRISPR perturbations, the authors investigate regulators of MYC in six different cancers. These tumor ...

Molecular Biology is the field of biology that studies the composition, structure and interactions of cellular molecules such as nucleic acids and proteins that carry out the biological ...

A research team led by Prof. Jiang Yanyi from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences has uncovered an important mechanism that enables squamous cell carcinoma (SCC ...