One of the outstanding problems in understanding optic nerve head dysfunction in glaucoma has been the elucidation of the pathways that could integrate the effects of lOP and ischaemia to generate ...

This pathway depends on the crossing of neurons ... into the narrow optic disc in the middle of the retina to form the optic nerve. These RGC axons then navigate toward the midline of the brain ...

In recent years, scientists have focused on developing neuroprotective drugs that can rescue RGCs and restore the optic nerve ...