C&EN18d
Design of Benzyl-triazolopyrimidine-Based NADPH Oxidase Inhibitors Leads to the Discovery of a Potent Dual Covalent NOX2/MAOB Inhibitor
Department of Drug Chemistry and Technologies, Sapienza University of Rome, P.le Aldo Moro 5, Rome 00185, Italy ...
scienceopen.com24d
Coumarin derivatives as inhibitors against monoamine oxidase: structure-activity relationships and inhibitory mechanisms
Mathew B, Haridas A, Uçar G, Baysal I, Adeniyi AA, Soliman ME, et al.. Exploration of Chlorinated Thienyl Chalcones: A New Class of Monoamine Oxidase-B Inhibitors. International Journal of Biological ...
Healthline27d
Factor VIII Assay
A factor VIII assay tests for a protein involved in blood clotting. If you produce less of this protein, it may indicate a bleeding disorder. Some people may also have high levels of this ...
C&EN1mon
Discovery of Novel N-Phenylphthalimide Protoporphyrinogen IX Oxidase Inhibitors
State Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Guiyang 550025, PR China ...
Frontiers3y
circSnx12 Is Involved in Ferroptosis During Heart Failure by Targeting miR-224-5p
The levels of MDA and iron in mouse heart tissues were measured using the Lipid Peroxidation (MDA) Assay Kit (ab118970, Abcam) and Iron Assay Kit (MAK025, Sigma-Aldrich), respectively, according to ...
Frontiers4y
Curcumin Protects Osteoblasts From Oxidative Stress-Induced Dysfunction via GSK3β-Nrf2 Signaling Pathway
Samples were incubated with newly prepared TUNEL assay solution 1h, then counterstained with 4′, 6-diamidino-2-phenylindole (DAPI, Sigma, United States) 5 min in the dark. Cells were observed by ...
eLife6y
Myocardial NADPH oxidase-4 regulates the physiological response to acute exercise
We identify the ROS-generating NADPH oxidase-4 (Nox4) as an essential regulator of exercise performance in mice. Myocardial Nox4 levels increase during acute exercise and trigger activation of the ...