Subsequently, S100A4 upregulates p53 expression, thereby promoting AML cell proliferation and resistance to Ara-C. Discussion: In summary, our comprehensive investigation of the ARRGRS not only ...

1Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas. *Corresponding Author: Guillermina Lozano, Department of Genetics, The University of Texas MD Anderson ...

This fundamental study identified a novel role of NOLC1 in regulating p53 nuclear transcriptional activity and p53-mediated ferroptosis in gastric cancer. After major revisions, the evidence ...

Comprehensive Cancer Center and Departments of Internal Medicine, Pharmacology, and Medicinal Chemistry, and Life Sciences Institute, University of Michigan, 1500 E. Medical Center Drive, Ann Arbor, ...

Elephants seem to have 20 different copies of a tumor-suppressing gene known as p53. This gene encodes a protein, also known as p53, which serves as a crucial cell protector. This protein acts a ...