In that environment, diseases could quickly spread. The first recorded pandemic caused by Yersinia pestis was the Plague of Justinian from 541 to 549 A.D. It killed nearly a fifth of the city of ...

and halted Justinian's dreams of reuniting the Roman Empire. In 396 BCE, as Carthaginian forces laid siege to Syracuse, a devastating plague erupted among their troops. The disease, intensified by ...

The Justinian plague definitely happened ... Smallpox (15th - 17th centuries) Europeans introduced a number of new diseases when they first arrived in the continents of the Americas in 1492.

In fact, scientists think that it may have been around before the 1300s, as there are records of a similar disease in Rome in 146AD, known as the Justinian plague. The symptoms of the plague were ...

In the wake of one of history's most devastating epidemics of bubonic plague, the Byzantine emperor Justinian enacts a ... With infectious diseases in mind, officials in Boston draw up an ...