Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and ...

Baloxavir marboxil, Endonuclease, by binding to the host RNA polymerase (Pol II segment) with the help of PB2 subunit cleaves ...

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...

This month's cover highlights the article Immune cells adapt to confined environments in vivo to optimise nuclear plasticity for migration by Helen Weavers and Tua Karling. The cover features confocal ...

Darnell discovered that when they put this exclusively human variant of NOVA1-an RNA-binding protein in the brain known to be crucial to neural development-into mice, it altered their ...

Get Instant Summarized Text (Gist) RNA in the Zika virus can maintain a stable configuration for extended periods, enhancing viral replication by protecting against host cell degradation. This ...

Then the RNA binding protein communicates to the splicing machinery to include or not include the exon into the mRNA,” Cooper explained. The fit between a splice site and the spliceosome components ...

If the changes you are trying to push are not registered on the client machine, then the registry could have a problem.pol file on the client or the Group Policy folder could be missing.

Guiding the process are short interfering RNAs (siRNAs) cut by DICER-LIKE 3 (DCL3) from double-stranded precursors of ~30 bp that are synthesized by NUCLEAR RNA POLYMERASE IV (Pol IV) and ...

Errors during transcription may play an important role in determining cellular phenotypes: the RNA polymerase error rate is >4 orders of magnitude higher than that of ...