An antibody discovery platform revealed more than 60 monoclonal antibodies specific to patients with alpha-gal syndrome, according to a poster presented here. This molecular characterization may ...

We examined alpha- and gamma-herpesvirus alterations to a type of alternative splicing, namely circular RNA (circRNA) synthesis. We developed “Circrnas in Host And viRuses anaLysis pIpEline” (CHARLIE) ...

Using an unbiased approach, this important study discovered a role of Ezh2 in the differentiation of granule neuron precursors, the cell of origin for Shh group of medulloblastoma. Furthermore, the ...

APAlyzer is a Bioconductor package which analyzes 3’UTR-APA and IPA based on annotated, conserved polyA sites at the recommended cutoff of relative expression between conditions (5%), using ...

However, NGS technologies are heavily limited by their inability to sequence long reads ... plain text files containing gene or isoform quantifications, polyA tail length estimations and RNA ...

Here, we report the molecular programmes and lineage progression patterns controlling human OA pathogenesis using single-cell RNA sequencing (scRNA-seq). Methods We performed unbiased ...

"NuFold can help bridge the gap by predicting the 3D structures of RNA from its sequence. By leveraging state-of-the-art machine learning techniques, NuFold can predict the full atomic structure ...

RNA-based therapeutics have rapidly emerged over the past decade, offering a new class of medicines that differ significantly from conventional drugs. These therapies can be programmed to target or ...

Replication-dependent (RD) core histone mRNA produced during S-phase is the only known metazoan protein-coding mRNA presenting a 3' stem-loop instead of the otherwise universal polyA tail. A metallo β ...