News

Novel assay promises more efficient screening for carriers of fragile X syndrome
Researchers have developed an innovative new nanopore sequencing assay to identify carriers of fragile X syndrome (FXS), the ...
Understanding us: Researchers apply algorithm to decode complex genome sequences
Over the last 10 years, breakthroughs in understanding the genetic instructions passed from parent to offspring have put ...
Imaging-based STAMP technique democratizes single-cell RNA research
Scientists at St. Jude Children's Research Hospital, the National Center for Genomic Analysis and the University of Adelaide ...
C&EN9d
Study of an RNA-Focused DNA-Encoded Library Informs Design of a Degrader of a r(CUG) Repeat Expansion
Department of Chemistry, UF Scripps Biomedical Research and The Scripps Research Institute, Jupiter, Florida 33458, United States Department of Chemistry and Pharmaceutical Sciences, University of ...
IEEE15d
Hybrid Causal Feature Selection for Cancer Biomarker Identification From RNA-Seq Data
In this work, we propose a novel hybrid causal feature selection method (called CAFES) to support large-scale cancer biomarker discovery from real RNA-seq data. Concretely, CAFES first uses ...
Carnegie Institution for Science16d
S1-DRIP-seq identifies high expression and polyA tracts as major contributors to R-loop formation
We report a novel whole-genome method, S1-DRIP-seq (S1 nuclease DNA: RNA immunoprecipitation with deep sequencing), for mapping hybrid-prone regions in budding yeast Saccharomyces cerevisiae. Using ...
AHA/ASA Journals17d
Disruption of cTnT-Mediated Sarcomere–Mitochondrial Communication Results in Dilated Cardiomyopathy
BACKGROUND: Dilated cardiomyopathy (DCM) is substantially influenced by genetic factors. Sarcomere function is intricately associated with other organelles, particularly the reciprocal regulation ...
C&EN28d
Sensitivity of the RNA Structure to Ion Conditions as Probed by Molecular Dynamics Simulations of Common Canonical RNA Duplexes
Regional Centre of Advanced Technologies and Materials, Czech Advanced Technology and Research Institute (CATRIN), Palacký University Olomouc, Šlechtitelů 27, 779 00 Olomouc, Czech Republic ...