Oxidative stress has long been implicated in cardiovascular disease, but more recently, the role of reactive oxygen species (ROS) in normal physiological signaling has been elucidated. Signaling ...

To investigate whether FCCP improved serine synthesis and proliferation of redox unresponsive cells through oxidizing ... HPA021241 [1:1000]), HSP90 (Cell Signaling Technology, 4874 [1:1000]), and ...

Background Chronic inflammation and elevated reactive oxygen species are key contributors to hepatocellular carcinoma (HCC) ...

New research reveals that aging isn't just a local cellular process—it can spread throughout the body via the bloodstream.

For the first time in the world, a Korean research team discovered how cellular aging can spread systemically through the ...

Redox regulation of proteins through oxidation and S-thiolation are important regulatory processes, acting in both a protective and adaptive role in the cell. In the current study, we investigated the ...

Researchers discovered that a redox-sensitive form of the protein HMGB1 circulates in the blood and spreads cellular ...

The reduction of a redox-active ligand is shown to drive reversible switching of a Cu(I) [2]pseudorotaxane ([2]PR+) into the reduced [3]pseudorotaxane ([3]PR+) by a bimolecular mechanism. The ...