Verve Therapeutics has started dosing patients in a phase 1b trial of its in vivo gene-editing drug for high cholesterol, designed to permanently switch off the PCSK9 gene with a one-shot ...

Amgen's Repatha (evolocumab) and Sanofi/Regeneron's Praluent (alirocumab) – given as once- or twice-monthly monthly injections – were hailed as blockbusters-in-waiting when they launched a few ...