Only one week remains in the NFL regular season and Week 18 will be played in after New Year's Day. We're on to 2025 and, of course, as the NFL Playoff picture ...

The NFC’s No. 1 seed, two division titles and two playoff spots are on the line in Week 18. Game No. 272 on Sunday night ...

The big prizes for the Detroit Lions remain on the horizon, with the team seeking a division title, the top seed in the NFC ...

Amon-Ra St. Brown and the Detroit Lions will visit George Kittle and the San Francisco 49ers on Monday at 8:15 p.m. ET, in a ...

In the NFC, wins for both the Detroit Lions and Minnesota Vikings set up a must-see Week 18 clash with the winner claiming ...

The Detroit Lions visit the San Francisco 49ers on Monday at 8:15 p.m. ET, in a matchup featuring a pair of the top offensive ...

James Conner and the Arizona Cardinals will host George Kittle and the San Francisco 49ers on Sunday at 4:25 p.m. ET, in a ...

The Detroit Lions will face the San Francisco 49ers in week 17 of the NFL season on Monday Night Football at Levi's Stadium ...

The last time the 49ers hosted the Detroit Lions, the stakes could hardly be higher. It was the NFC title game, and the 49ers ...

The Detroit Lions got their revenge on the San Francisco 49ers. Here are winners and losers from the Week 17 Monday Night Football clash.

Before kickoff between the Detroit Lions and San Francisco 49ers on MNF, veteran DE Za'Darius Smith had an NSFW for the home ...

Live score updates, highlights, and injury news from Detroit Lions vs. San Francisco 49ers on “Monday Night Football.” ...