This content was created by our physicians and experts. By Alana C. Serota, MD, CCFP, CCD Osteoporosis has been called a "silent" disease because the loss of bone progresses gradually without pain or ...

De-Escalation of Bone-Modifying Agents in Patients With Bone Metastases: The Best of Times and the Worst of Times? The bone-modifying agents zoledronic acid, pamidronate, and denosumab have essential ...