Steitz and Vasudevan have previously identified two key components for translational upregulation during serum starvation: the proteins argonaute 2 (Ago 2) and fragile-X-metal retardation related ...
Sparse cultures of embryonic fibroblasts were synchronized in the G 0 portion of the cell cycle by serum starvation and then placed under either low (2.5%) or ambient (20%) oxygen for 24 hours.