When people think of DNA, they usually think of genes, the parts that code for proteins and drive inherited traits. But there ...

A deeper understanding of how DNA changes over generations helps scientists learn why people differ and how diseases develop.

Scientists push single-molecule DNA sequencing to the next level Two new tools created at Gladstone Institutes allow scientists to study DNA at single-molecule resolution using fewer cells than ...

They want longer, more complex DNA sequences (even whole genomes), and they want high accuracy (down to a single base). But longer, more complex sequences often need to be put together from scratch.

Human DNA contains roughly 3 billion letters of genetic code. However, we understand only a fraction of what this vast ...

Powerful new applications of what is known as next-generation sequencing are now helping with identification of degraded ...

PacBio describes the sequencer as an improvement over its current high-capacity Sequel IIe long-read hardware. Though both rely on what the company has dubbed HiFi sequencing, the Revio includes a ...

Over the past decade, reads—the product of DNA sequencing—have been getting longer. Long-read sequencing has allowed scientists to sequence troublesome “dark regions” of the genome that are ...

The DNA bricks were then typeset onto the DNA template in a fixed sequence, each brick containing a single bit of information (called an epi-bit) in the form of a 0 or 1.

An STR is a short sequence of base-pairs on the DNA that is repeated some number of times, such as GATCGATCGATCGATC (on the complementary strand, this STR will have the sequence CTAGCTAGCTAGCTAG ...