New precision genome editing technologies are transforming the therapeutic landscape for patients with certain cancers and ...

CD47-amyloid-β-CD74 signaling is a key driver of adaptive immunosuppression in sepsis, suppressing B cells and impairing ...

A new suggestion that complexity increases over time, not just in living organisms but in the nonliving world, promises to ...

Signature genes were further validated in specific subsets using single-cell RNA sequence data. Finally, molecular docking and molecular dynamics simulation were conducted to evaluate interactions ...

Oncogene permanent activation in a single targeted cell of zebrafish together with a reprogramming factor transient activation is sufficient to induce the malignant transformation of the cell and ...

Single-cell RNA sequence revealed that APOEε4 led to a significantly less gene expression of the GLRA1 gene in Sst chodl neurons and KCNA1 gene in L5/6 NP neurons. The present findings provide insight ...

Single-cell RNA sequence revealed that APOEε4 led to a significantly less gene expression of the GLRA1 gene in Sst chodl neurons and KCNA1 gene in L5/6 NP neurons. The present findings provide insight ...

Institute of Systems and Physical Biology, Shenzhen Bay Laboratory, Shenzhen 518055, China School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, ...

Using so-called RNA aptamers, the artificial cytoskeleton was bound to the cell membranes. Through targeted mutations to the genetic template—the DNA sequence—it was also possible to influence ...

Their findings, published in Molecular Cell March 17, could open new pathways ... researchers found that ADAR1's editing activity depends on RNA sequence, duplex length and mismatches near the ...