Within healthy and inflamed intestinal tissues, single-cell omics, particularly single-cell RNA sequencing, have contributed to uncovering novel cell types and cell functions linked to disease ...

Q-rH, J-jM, and L-yZ prepared the nuclei sample and performed the single-nuclei RNA-seq. S-jQ, L-yZ, and R-yC performed functional validation. S-jQ, Q-rH, H-cL, and BL wrote the manuscript with input ...

Here, single-cell RNA sequencing (scRNA-seq) was used to identify various meniscus cell subsets and investigate the mechanism of meniscus degeneration. Methods scRNA-seq was used to identify cell ...

Here, we report a systematic transcriptional atlas to delineate molecular and cellular heterogeneity in GA using single-cell RNA sequencing (scRNA-seq). Design We performed unbiased transcriptome-wide ...

Data normalization is vital to single ... in bulk sequencing, designed to be resistant to outliers (Li and Tibshirani, 2011). It uses the two-sample Wilcoxon test and Poisson resampling to detect the ...

The ST Pipeline can also be used to process single cell/nuclei RNA-seq data as long as a file with molecular barcodes identifying each cell is provided (same template as the files in the folder "ids") ...

This requirement is known as crossover assurance and is one example of crossover control. While the conserved role of the ATPase, PCH-2, during meiotic prophase has been enigmatic, a universal ...