ALLEN PARK -- Alex Anzalone and Terrion Arnold are officially questionable to play on Sunday against the Arizona Cardinals. Both players made limited returns to practice this week and are trending toward playing in the desert, while defensive backs Ifeatu Melifonwu and Ennis Rakestraw have been ruled out.

The Detroit Lions' Thursday injury report leading to Sunday’s game against the Arizona Cardinals resulted in three players upgraded from their Wednesday status. The full details are below. Detroit Lions Week 3 Thursday injury report Did not participate CB

Linebacker Alex Anzalone suffered a brain injury after taking a shot to the head from teammate Derrick Barnes in the 20-16 loss against Tampa. He’s now in concussion protocol, but already feeling better heading into the practice week for Sunday’s matchup against the Arizona Cardinals.

Should Alex Anzalone miss Sunday's game due to a concussion, Coach Dan Campbell's confidence is high in second-year linebacker Jack Campbell.

Detroit Lions LB Alex Anzalone had brain injury in helmet-to-helmet collision; Dan Campbell downplayed concern on Amon-Ra St. Brown & Terrion Arnold.

For the Lions, the only starter I'm expecting to be out is Alex Anzalone. Otherwise, the Lions are healthy heading into Arizona. The Cardinals started the week with a tiny injury report but had two players suffer new hamstring injuries during the week that could