with anti-Myc antibody. UbcH7 and, faintly, UbcH8 were co-immunoprecipitated with parkin, but no appreciable binding was observed for any other E2 enzymes examined, such as Ubc2, Ubc3, Ubc4 ...

State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China Center for Translational Medicine, The ...

The oncoprotein transcription factor MYC is a major driver of malignancy and a highly validated but challenging target for the development of anticancer therapies. Novel strategies to inhibit MYC may ...

HEK293 T cells were maintained at 37°C in a humidified incubator containing 5% CO 2 ... and the expression of Myc-nedd8 was confirmed by Western blot using anti-Myc antibody (9E10, Santa Cruz).