The 49ers are likely to be without Christian McCaffrey, Deebo Samuel and now George Kittle against the Rams on Sunday ...

Suddenly in doubt for the Week 3 game at L.A. are tight end George Kittle, defensive end Nick Bosa, and cornerback Charvarius ...

For San Francisco, tight end George Kittle (hamstring) is doubtful, defensive end Nick Bosa (rib) and cornerback Charvarius ...

Bosa (ribs) has been deemed questionable to play Week 3 versus the Rams, Matt Barrows of The Athletic reports.

George Kittle is doubtful for Sunday's game at Los Angeles with a hamstring injury, while two of San Francisco's top ...

Nick Bosa has job stress. A lot of it. The San Francisco 49ers’ generational pass rusher has coped by becoming a voracious reader and dabbling in meditation. He has visited with the team’s ...

After a strong start with a 32-19 win against the New York Jets in Week 1 and the 23-17 loss against the Minnesota Vikings, ...

San Francisco 49ers linebackers Demetrius Flannigan-Fowles and Curtis Robinson joined the 49ers "You've Got Mail" podcast ...

After an upset loss to the Minnesota Vikings in Week 2, the three 49ers most to blame are Jake Brendel, Brandon Aiyuk, and ...

Injuries are an inherent part of the game of football, and the San Francisco 49ers are feeling the effects as they prepare ...

Mack, standing 6-foot-3, 270 pounds and a three-helmet guy to this point, had perhaps his best season last year, putting up a ...