The last time the Los Angeles Rams and San Francisco 49ers met, head coaches Sean McVay and Kyle Shanahan were without some starters. That was Week 18 of the 2023 season, and both teams had already clinched playoff berths.

The 49ers and Rams meet in NFC West action, but both teams are going to look like shells of its best form. Injuries have taken its toll on both the 49ers and R

There may not be two teams more injured than the Los Angeles Rams and San Francisco 49ers, which will have a big impact on Sunday’s game at SoFi Stadium. The 49ers are missing Christian McCaffrey, Deebo Samuel and possibly George Kittle, while the Rams will be without Cooper Kupp, Puka Nacua and two starting offensive linemen.