There are 4 ways to get from St. Louis to Columbus by bus, taxi, car, or plane. Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Mar 31, 2023 · If you’re going on a road trip from Columbus to Saint Louis, we did the research for you and compiled some great stops along the way — with Indianapolis, Dayton, and Bloomington, as well as top places to visit like Frank Lloyd Wright's Westcott House and Young's Jersey Dairy, or the ever-popular Ohio Caverns.

Choose from almost 2,300 destinations with Greyhound, FlixBus and our connecting partners! Book your next Greyhound bus from Columbus, IN to St Louis, MO. Get free Wi-Fi & plug outlets on board, extra legroom and 2 pieces of free luggage.

Apr 10, 2023 · If you’re going on a road trip from Columbus to Saint Louis, we did the research for you and compiled some great stops along the way — with Indianapolis and Bloomington, as well as top places to visit like Ruoff Music Center and Conner Prairie, or the ever-popular Horseshoe Indianapolis, Shelbyville.

Get a quick answer: It's 284 miles or 457 km from Columbus (Indiana) to St. Louis, which takes about 4 hours, 15 minutes to drive.

Here's a sample itinerary for a drive from Columbus (Indiana) to St. Louis. If you're planning a road trip to St. Louis, you can research locations to stop along the way. Make sure you check road conditions to double check the weather.

There are 6 ways to get from St. Louis Airport (STL) to Columbus by plane, taxi, bus, or car. Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

The cheapest way to get from Columbus to St. Louis costs only $63, and the quickest way takes just 4¾ hours. Find the travel option that best suits you.

The total driving distance from Columbus, IN to Saint Louis, MO is 284 miles or 457 kilometers. Your trip begins in Columbus, Indiana. It ends in Saint Louis, Missouri.

Check the road conditions from St. Louis to Columbus (Indiana) and plan a trip based on the weather along the way.