About HHMI | Howard Hughes Medical Institute
The Howard Hughes Medical Institute (HHMI) advances the discovery and sharing of scientific knowledge to benefit us all. Founded in 1953, HHMI is a biomedical research organization and philanthropy with a vibrant community of researchers, educators, students, and professionals.
HHMI: Advancing Scientific Research & Education
HHMI is expanding the frontiers of science, research culture, and science education. Explore our research, educational initiatives, and partnerships.
Investigator Program | HHMI
We believe that the most transformative breakthroughs come when talented scientists are given the freedom to pursue bold ideas. That’s why we take a “people, not projects” approach, providing generous and flexible support to talented scientists so they can go where their science leads.
Jonathan Abraham, MD, PhD | Investigator Profile | 2024-Present
Jonathan Abraham studies how viruses infect cells and replicate their genomes. His lab uses molecular virology and structural biology methods to study how viral spike proteins bind to receptors when infecting cells, how neutralizing antibodies block viral infection, and – once viruses infect cells – how viral polymerases replicate and/or transcribe viral genomes.
Hanna H. Gray Fellows Program | HHMI
Supporting early career scientists as they launch careers in academic science, and equipping them to recruit, mentor, and inspire future generations. Fellows join a cohort of peers and receive funding up to $1.5 million.
Targeting Rett Syndrome, Alzheimer’s Disease | HHMI
Oct 23, 2024 · More than 30 years ago, as a pediatric resident at Texas Children’s Hospital and the Baylor College of Medicine, Huda Zoghbi first encountered patients with symptoms of a rare neurodevelopmental disorder that leads to a progressive loss of mobility and coordination early in a child’s life. In time, each patient’s story inspired Zoghbi to pivot from clinical medicine to research, where ...
Modern Europeans Descended from Three Groups of Ancestors
Sep 17, 2014 · HHMI scientists have shown that previously unrecognized groups contributed to the genetic mix now present in most modern-day Europeans.
2024 Investigator Competition FAQ - HHMI
HHMI’s community of basic researchers and physician scientists bring innovative approaches to the study of biological problems in basic and biomedical sciences, plant biology, evolutionary biology, biophysics, chemical biology, biomedical engineering, and computational biology.
Samuel H. Sternberg, PhD | Investigator Profile | 2024-Present
Samuel Sternberg’s lab is broadly interested in discovering diverse, programmable functions of non-coding RNA molecules in the cell. From guiding the site-specific insertion of DNA transposons, to targeting foreign pathogens for DNA cleavage, to templating the synthesis of novel antiviral genes, RNAs direct remarkably complex biochemical reactions in coordination with accessory enzymes.
Fellowship Term Begins September 1, 2025 Application Opens October 17, 2024 Application Deadline December 5, 2024 Award Notification June 2025 2025 Program Announcement