Rheumatoid arthritis - Latest research and news | Nature
6 days ago · Rheumatoid arthritis is an autoimmune disease that is characterized by inflammation of the joints and the subsequent destruction of cartilage and erosion of the bone.
Striking a balance in rheumatoid arthritis prevention trials
May 7, 2021 · The discovery that autoantibodies and other factors can predict the future onset of rheumatoid arthritis (RA) has encouraged the development of clinical trials looking at RA prevention.
Rheumatoid arthritis | Nature Reviews Disease Primers
Feb 8, 2018 · This Primer by Smolen et al. provides the latest insights into the epidemiology, genetics, pathophysiology, diagnostic approaches, clinical assessment and management of rheumatoid arthritis.
Rheumatoid arthritis: pathological mechanisms and ... - Nature
Apr 27, 2018 · Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that arises more frequently in females than males, being predominantly observed in the elderly.
2021 ACR guideline reflects changes in RA treatment
Jul 16, 2021 · The 2021 ACR guideline for the treatment of rheumatoid arthritis provides an update on several important topics, including the use of targeted synthetic DMARDs (tsDMARDs).
Rheumatoid arthritis | Nature Reviews Rheumatology
Sep 25, 2024 · Pathogenic antibodies target stromal antigens in RA. New findings identify HSP60 and other synovial stromal-derived autoantigens as targets for pathogenic autoantibodies, exacerbating arthritis ...
Rheumatology - Latest research and news | Nature
Nov 6, 2024 · JAK inhibitors improve RA pain. Consistent with findings from clinical trials, in a retrospective cohort study, Janus kinase inhibitors improved pain associated with rheumatoid arthritis as well ...
Immunotherapy for rheumatoid arthritis - Nature
May 30, 2023 · Activating the PD-1 checkpoint might reset the immune system and reduce disease activity in patients with rheumatoid arthritis, according to a phase 2a trial.
Signaling pathways in rheumatoid arthritis: implications for ...
Feb 17, 2023 · Treatment for rheumatoid arthritis could help relieve pain, reduce joint inflammation, prevent or slow joint injury, reduce disability and keep patients as active as possible.
BiTE therapy for rheumatoid arthritis | Nature Medicine
Apr 26, 2024 · Nature Medicine - A pilot study suggests that the bispecific T cell engager blinatumomab may provide a new therapy for patients with refractory rheumatoid arthritis; larger studies and deep ...